Prospective, randomized, double-blind trial to investigate the efficacy and safety of corneal cross-linking to halt the progression of keratoconus.

Background: Corneal cross-linking is widely used to treat keratoconus. However, to date, only limited data from randomized trials support its efficacy.

Methods: The efficacy and safety of corneal cross-linking for halting progression of keratoconus were investigated in a prospective, randomized, blinded, placebo controlled, multicentre trial.

Three-dimensional posterior segment ultrasonography: clinical experience.

Purpose: To introduce a commercially available three-dimensional ultrasonography unit into everyday clinical practice and to evaluate the qualitative and quantitative information of the acquired images and to clarify the indications for 3-D echography.

Materials And Methods: 3-D scanning was performed on 59 referred patients with indications for conventional B/A-scan. On 7 patients with an intraocular mass with well-delineated borders 10 repeated volume measurements were carried out.