Publications by authors named "B Kulzer"

Inflammation is a probable biological pathway underlying the relationship between diabetes and depression, but data on differences between diabetes types and symptom clusters of depression are scarce. Therefore, this cross-sectional study aimed to compare associations of a multimarker panel of biomarkers of inflammation with depressive symptoms and its symptom clusters between people with type 1 diabetes (T1D) and type 2 diabetes (T2D). This cross-sectional study combined data from five studies including 1260 participants (n = 706 T1D, n = 454 T2D).

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Aim: To analyse the potential drivers (glucose level, complications, diabetes type, gender, age and mental health) of diabetes symptoms using continuous glucose monitoring (CGM) and ecological momentary assessment.

Materials And Methods: Participants used a smartphone application to rate 25 diabetes symptoms in their daily lives over 8 days. These symptoms were grouped into four blocks so that each symptom was rated six times on 2 days (noon, afternoon and evening).

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Article Synopsis
  • - This systematic review and meta-analysis investigated the impact of automated insulin delivery (AID) systems on person-reported outcomes (PROs) in diabetes management, compiling data from 62 studies with over 9,200 participants.
  • - The findings revealed that AID systems significantly decreased diabetes distress, fear of hypoglycemia, and improved quality of life for both adults and children/adolescents, based on data from randomized controlled trials and observational studies.
  • - Overall, the study suggests that AID therapy can lead to positive outcomes for individuals with diabetes, highlighting its potential benefits despite the varying effect sizes.
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The last 25 years of CGM have been characterized above all by providing better and more accurate glucose values in real time and analyzing the measured glucose values. Trend arrows are the only way to look into the future, but they are often too imprecise for therapy adjustment. While AID systems provide algorithms to use glucose values for glucose control, this has not been possible with stand-alone CGM systems, which are most used by people with diabetes.

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