[Albumin and immunoglobulin levels in cerebrospinal fluid and serum in tick borne meningoencephalitis].

The levels of albumin and immunoglobulins G, A, M were determined by using nephelometry technique in the cerebrospinal fluid and serum in 14 adults with tick borne meningoencephalitis at the beginning and after four weeks of disease. Intra blood-brain synthesis of IgG, IgA, IgM was evaluated by indexes of synthesis (Tibbling formula). The blood-brain integrity was estimated by CSF/serum albumin ratio.

Assessment of beta-2-microglobulin concentration in serum and urine in rheumatoid arthritis.

Assessment of beta-2-microglobulin (beta-2-M) concentration in serum and urine was made in 50 patients with rheumatoid arthritis (RA). The most often noticed pathology was proteinuria. We observed a significant increase of beta-2-M concentration in serum of patients without rheumatoid factor and in patients with proteinuria.

[Role of hematopoietic factors in regulation of proliferation and function of phagocytes].

Hematopoietic growth factors belong to the family of glycoproteins responsible for regulation, differentiation and proliferation of myelopoietic cells. In this paper the role of these factors in regulation of the function of phagocytic cells (granulocyte, monocyte, macrophage) is discussed on the basis of literature data.

[Value of the study of total alkaline phosphatases and bone isoenzyme in a population of subjects with osteoporosis].

The authors have compared the values of total and bone serum alkaline phosphatases in an osteoporotic population and a control group. The total activity of alkaline phosphatases was determined by a kinetic method at 30 degrees C and alkaline phosphatase isoenzymes were separated by agarose gel electrophoresis in presence or absence of wheat germ lectin. The authors have confirmed reported data concerning the physiological variations of alkaline phosphatases in the control group; they have therefore divided each group in several sub-populations according to age and sex in order to obtain accurate comparisons.