Clinical trials on adjuvant chemotherapy for breast cancer.

Clinical trial initiated in 1975 at the Petrov Research Institute of Oncology (Leningrad) included 1228 patients with breast cancer Stages I, II, and III. Adjuvant chemotherapy in patients with Stages I-II (P T0-2N0-1M0) leads to decrease in mortality rate by 24.3% in the case of monochemotherapy (thiotepa, six courses, 200 mg each course) and 32.

End results of treatment of breast cancer patients.

Data are presented on 3359 breast cancer patients treated at the Petrov Research Institute of Oncology of the USSR Ministry of Health. For the 20-year period (from 1955 to 1975) not large but statistically significant increase of the 5-year survival was noted which achieved 64.7% in 1971-1975.

[Long-term results of treatment of 3,359 patients with breast cancer].

The paper presents the data on 3359 cases of breast cancer treated at the Institute. A slight (4.7-7.