Publications by authors named "B Koloko"

Article Synopsis
  • - The study evaluated the effects of Vepris afzelii root extract on male rats with hypogonadism induced by cyproterone acetate, showing significant alterations in sexual behavior and reproductive parameters after treatment.
  • - The experiment included 36 adult Wistar rats divided into groups, with some receiving distilled water, testosterone, or varying doses of the extract over a 14-day period.
  • - Key findings indicated significant reductions in sexual activity, sperm mobility, and testosterone levels in hypogonadal rats, while treatment with the extract improved several reproductive metrics compared to controls.
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The enhancement of CRISPR-Cas gene editing with robust nuclease activity promotes genetic modification of desirable agronomic traits, such as resistance to pathogens, drought tolerance, nutritional value, and yield-related traits in crops. The genetic diversity of food crops has reduced tremendously over the past twelve millennia due to plant domestication. This reduction presents significant challenges for the future especially considering the risks posed by global climate change to food production.

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Plants and plant-derived products have a long history in the treatment of sexual disorders. Rauvolfia vomitoria is one of such plant used traditionally for the enhancement of male sexual and reproductive activity. This study was carried out to elucidate the potential activity of R.

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The effect of the methanolic extract of Alchornea cordifolia leaves on the fertility of senescent male rats was assessed in this study. 40 rats received daily distilled water, testosterone, 200 and 400 mg/kg of extract of Alchornea cordifolia. The reproductive organs weight, the gonadotropins, testosterone and cholesterol level, the sperm parameters, histology of the testes and epididymis were assessed.

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