The History and Impact of Prescribing Orthokeratology for Slowing Myopia Progression.

This paper discusses the history and impact of orthokeratology on slowing the progression of myopia. It discusses the origins and evolution of orthokeratology from polymethymethaccrylate lenses worn during the day to its current prescribing of highly permeable, innovative reverse-geometry designs worn only while sleeping. Technological advances in corneal topography, lens design, lens materials, and manufacturing have facilitated growth of orthokeratology to a precise and predictable procedure.

Contact Lens Safety for the Correction of Refractive Error in Healthy Eyes.

Contact lenses are a safe and effective method for correction of refractive error and worn by an estimated 45 million Americans. Because of the widespread availability and commercial popularity of contact lenses, it is not well appreciated by the public that contact lenses are U.S.

The Role of Orthokeratology in Myopia Control: A Review.

The prevalence of myopia and high myopia has significantly increased worldwide and in the United States. The serious implications of these trends are being recognized. Myopia is not just a minor inconvenience requiring vision correction with glasses or contact lenses, but a disease process creating significant risk of serious vision-threatening eye disease.

Success Rate of Incorporating Corneal Refractive Therapy into 3 Different Ophthalmology Practices.

Objective: The purpose of the study was to evaluate the efficacy of orthokeratology in correcting myopia.

Methods: The study took place over three ophthalmology practices, which were trained in fitting corneal reshaping therapy lenses. The patients' age ranged from 9 to 59 years.

Compartment specific response of antioxidants to drought stress in Arabidopsis.

Compartment specific changes in ascorbate and glutathione contents were studied during drought stress in Arabidopsis thaliana Col-0 and in ascorbate and glutathione deficient mutants vtc2-1 and pad2-1, respectively, over a time period of 10 days. The results of this study revealed a strong decrease of glutathione contents in both mutants (up to 52% in mitochondria of pad2-1 and 40% in nuclei of vtc2-1) at early time points when drought stress was not yet measurable in leaves even though the soil showed a drop in relative water contents. These results indicate that glutathione is used at early time points to signal drought stress from roots to leaves.