Publications by authors named "B Kniazewski"

The problem of breast cancer during pregnancy was touched. Usually in pregnant women with breast cancer the prognosis is bad. Authors described 3 cases of pregnant patients with breast cancer.

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Objectives: The presence of adnexal tumours in pregnancy is a significant problem for obstetricians requiring quick diagnosis and operation.

Materials And Methods: The paper presents 22 cases of ovarian tumours diagnosed and treated during pregnancy. In 12 cases laparoscopical cystectomies were performed, in 10 cases laparotomies were done.

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Genetic factors have been reported to play an important role in the predisposition to development of pregnancy-induced hypertension (PIH). On the other hand, there is strong evidence that genetic factors play important role in the predisposition to essential hypertension. Recently, the plausible "candidate gene" for the development of hypertension is SA gene.

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Objective: The aim of our study was to evaluate the relation of parental history of hypertension to the development of PIH, and to assess the potential role of plausible candidate loci in the susceptibility to PIH.

Study Design: Five polymorphisms: ACE gene I/D and Pst1 RFLP polymorphism, AGT gene M235T polymorphism, AGTR1 gene A1166C polymorphism, and chymase gene CMA/B polymorphism were studied in 126 women suffering from PIH in comparison with 150 healthy pregnant women. Genotyping was performed using methods based on polymerase chain reaction.

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Genetic and familial factors may predispose to H-gestosis. The aim of our study was to answer the question if angiotensinogen gene m235t polymorphism, and ACE gene I/D and Pst I RFLP polymorphisms may be markers of genetic predisposition to the H-gestosis. 246 pregnant women (median age 26 years) were studied (the studied group consisted of 116 women with H-gestosis and the control group consisted of 130 healthy pregnant women).

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