Stimulated monocyte IL-6 secretion predicts survival of patients with head and neck squamous cell carcinoma.

Background: This study was performed in order to determine whether monocyte in vitro function is associated with presence, stage and prognosis of head and neck squamous cell carcinoma (HNSCC) disease.

Methods: Prospective study describing outcome, after at least five years observation, of patients treated for HNSCC disease in relation to their monocyte function. Sixty-five patients with newly diagnosed HNSCC and eighteen control patients were studied.

Time patterns of changes in biomarkers, symptoms and histopathology during pelvic radiotherapy.

Acute radiation proctitis was evaluated before, during and after radiotherapy (RT) for prostate cancer. The main aims of the study were to examine changes related to the increasing radiation dose, and identify surrogate markers of gastrointestinal (GI) reaction to radiation. Twenty consecutive prostate cancer patients scheduled for 7 weeks of conformal RT were prospectively included in a longitudinal study assessing symptoms, inflammation in rectal mucosa biopsies, and blood and stool samples at four time points (before RT and 2, 6 and 11 weeks after start of RT).

Presence of activated T lymphocytes in peripheral blood of head and neck squamous cell carcinoma patients predicts impaired prognosis.

Conclusions: The results indicate that a high level of peripheral blood (PB) T-lymphocyte activation in vivo predicts impaired prognosis with and without adjustment for TNM stage in head and neck squamous cell carcinoma (HNSCC).

Objective: To determine if PB T-lymphocyte activation in vivo is associated with the presence of, stage of and prognosis of HNSCC.

Materials And Methods: Sixty-two patients with newly diagnosed HNSCC and 15 control patients were studied.

[Fish--more than just omega 3].

In the Norwegian governmental guidelines for food and nutrition, an increased intake of fish and other seafood is particularly recommended. Fish is a good source of many important nutrients, such as proteins, very long-chain omega 3 fatty acids, vitamin D, vitamin B12, selenium and iodine. The beneficial effect on health by including fish has been documented in several studies.

Reduced joint pain after short-term duodenal administration of seal oil in patients with inflammatory bowel disease: comparison with soy oil.

Background: Rheumatic joint pain is a common extra-intestinal complication of inflammatory bowel disease (IBD). Because the high ratio of n-6 to n-3 fatty acids (FAs) of the Western diet might promote rheumatic disorders, we sought to compare the effects of short-term duodenal administration of n-3-rich seal oil and n-6-rich soy oil on IBD-related joint pain.

Methods: Nineteen patients with IBD-related joint pain were included in the study; 9 had Crohn disease and 10 had ulcerative colitis.