Magnetic nanoparticles as a drug delivery system that enhance fungicidal activity of polyene antibiotics.

This study was designed to assess the antifungal/anti-biofilm and hemolytic properties of two polyene antibiotics, amphotericin B (AMF) and nystatin (NYS), attached to the surface of magnetic nanoparticles (MNP) against clinical isolates of Candida species and human red blood cells, respectively. The developed nanosystems, MNP@AMF and MNP@NYS, displayed stronger fungicidal activity than unbound AMF or NYS. Synergistic activity was observed with a combination of polyenes and MNPs against all tested Candida strains.

Environmental contamination with Toxocara eggs and seroprevalence of toxocariasis in children of northeastern Poland.

Toxocariasis is a worldwide distributed zoonotic disease. Soil contaminated with Toxocara eggs appears to be the main source of infection for humans. The aim of our study was to estimate the environmental contamination with Toxocara eggs in public areas in northeastern Poland followed by the assessment of seroprevalence of toxocariasis in the children's population inhabiting the areas.

Occurrence of fungi and fungus-like organisms in the Horodnianka River in the vicinity of Białystok, Poland.

Studies of fungi and fungus- like organisms in the northeastern Poland have mainly concentrated on running waters in the vicinity of Białystok, including the Horodnianka River. The main objective was to investigate biodiversity of fungi and fungus-like organisms which take part in decomposition of organic matter commonly found in inland waters. To obtain a complete picture of species composition of fungi and fungus-like organisms in running waters we decided to explore representative sites of the Horodnianka River such as Olmonty, Hryniewicze and Horodniany with close localization of landfill.

[Occurrence and morphology of some predatory fungi, amoebicidal, rotifericidal and nematodicidal, in the surface waters of Białystok region].

Studies concerned the occurrence of some predatory fungi in the surface waters: springs, rivers, lakes and ponds of Białystok region, collected in years 1999-2002. The following species of predatory fungi, amoebicidal, rotifericidal and nematodicidal were found: Arthrobotrys oligospora Fresenius, Zoophagus insidians Somlnestorff, Somnuerstorffia spinosa Arnaudov, Dactylaria brochopaga Drechsler, Euryancale sacciospora Dreschler and Zoopage phanera Drechsler. Physico-chemical parameters of waters in basins and water-courses did not prove important effect on existence of fungi.

[Aspects of ecological occurrences Trichosporon cutaneum (de Beurman Gougerot et Vaucher, 1909 ota, 1915) in waters north-east Polands].

The aim of work was settlement of occurrence of pathogenic fungus Trichosporon cutaneum in diverse ecological environments. Object to investigations former river Wegorapa, Supraśl, lakes of complex Mamry and Sejny group, of cultivation ponds in Popielewo and in Poryte Jabłoń a few springs of city Białystok. In investigations one used method of baits to isolated water fungus.