Publications by authors named "B Khoshnood"
Article Synopsis
- Congenital ocular anomalies (COA) are a leading cause of visual impairment in children in high-income countries, and this study aimed to evaluate their prevalence in European registries.
- Data from 19 EUROmediCAT registries and one healthcare database revealed a prevalence of COA at 3.47 cases per 10,000 births, with congenital lens anomalies being the most common type.
- The findings suggest the need for better screening and early diagnosis of COA, highlighting the importance of large-scale epidemiological studies for understanding these conditions.
Article Synopsis
- - The study investigated the impact of prolonged extreme heat exposure during early pregnancy (specifically during the August 2003 heatwave in France) on the risk of neural tube defects (NTDs) in newborns.
- - Researchers analyzed data from the Paris Registry of Congenital Malformations, finding that out of 1272 NTD cases recorded between 1994 and 2018, ten cases were linked to conceptions during the extreme heat period, showing a significantly higher risk (relative risk = 2.14).
- - Overall, the findings indicate that exposure to extreme heat in the early stages of pregnancy is associated with an increased risk of NTDs, highlighting potential environmental health risks during critical periods of fetal development.
Objective: To assess the frequency of fetal therapy for fetuses with congenital pulmonary malformations (CPMs) and to investigate their short-term outcomes.
Method: The study population included 435 singleton fetuses diagnosed with CPMs from a national population-based cohort study in France in 2015-2018. Information was obtained from medical records on CPM volume ratio (CVR), signs of compression, fetal therapy and perinatal outcomes.
Article Synopsis
- Registries of congenital anomalies (CAs) provide important data for monitoring CAs, and a study analyzed the prevalence and related outcomes in Paris from 1981 to 2020.
- The prevalence of CAs remained stable at around 2.9% of total births, with genetic anomalies being the most common, while prenatal diagnoses significantly increased from about 17% to 70%.
- Infant mortality rates varied by condition, reaching as high as 86% for hypoplastic left heart syndrome, indicating differing outcomes based on the type of anomaly.
Article Synopsis
- Congenital heart defects (CHDs) are the most common congenital anomalies, affecting almost 1% of newborns, and vary widely in severity and treatment.
- The study aimed to analyze long-term survival rates in newborns with CHD and to create predictive models for infant mortality using the Anatomic and Clinical Classification of CHD (ACC-CHD).
- Results showed an overall 8-year survival rate of 96% for isolated CHDs, with survival rates differing significantly among categories, from 99.5% for some conditions to as low as 34% for more severe cases.