Publications by authors named "B Khalesi"
Article Synopsis
- Pancreatic cancer presents challenges such as unusual symptoms, rapid progression, and a lack of reliable early diagnostic methods and effective treatments.
- Research indicates that exosomes (tiny vesicles secreted by cells) could play significant roles in diagnosing and treating pancreatic cancer, as they may serve as less invasive liquid biopsies and drug carriers.
- While current studies show promise for using exosomes in early diagnosis and monitoring, more research and clinical trials are needed before they can become standard tools for managing pancreatic cancer.
Microwave imaging for breast cancer screening: protocol for an open, multicentric, interventional, prospective, non-randomised clinical investigation to evaluate cancer detection capabilities of MammoWave system on an asymptomatic population across multiple European countries.
BMJ Open
November 2024
Introduction: Microwave imaging presents several potential advantages including its non-ionising and harmless nature. This open, multicentric, interventional, prospective, non-randomised trial aims to validate MammoWave's artificial intelligence (AI)-based classification algorithm, leveraging microwave imaging, to achieve a sensitivity exceeding 75% and a specificity exceeding 90% in breast screening.
Methods And Analysis: 10 000 volunteers undergoing regular mammographic breast cancer screening will be recruited across 9 European centres and invited to participate in the clinical study, involving MammoWave testing on both breasts.
Acinetobacter baumannii, is among the highest priority bacteria according to the WHO categorization which necessitate the exploration of alternative strategies such as vaccination. OmpA, BamA, and Omp34 are assigned as appropriate antigens to serve in vaccine development against this pathogen. Experimentally validated exposed epitopes of OmpA and Omp34 along with selected exposed epitopes predicted by an integrative in silico approach were represented by the barrel domain of BamA as a scaffold.
View Article and Find Full Text PDFExosomes play a key role in colorectal cancer (CRC) related processes. This review explores the various functions of exosomes in CRC and their potential as diagnostic markers, therapeutic targets, and drug delivery vehicles. Exosomal long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) significantly influence CRC progression.
View Article and Find Full Text PDFBackground: Renal Cell Carcinoma (RCC) stands as a formidable challenge within the field of oncology, despite considerable research endeavors. The advanced stages of this malignancy present formidable barriers to effective treatment and management.
Objective: This review aims to explore the potential of exosomes in addressing the diagnostic and therapeutic challenges associated with RCC.