Publications by authors named "B Kendzia"
Background: Increased lung-cancer risks for low socioeconomic status (SES) groups are only partially attributable to smoking habits. Little effort has been made to investigate the persistent risks related to low SES by quantification of potential biases.
Methods: Based on 12 case-control studies, including 18 centers of the international SYNERGY project (16,550 cases, 20,147 controls), we estimated controlled direct effects (CDE) of SES on lung cancer via multiple logistic regression, adjusted for age, study center, and smoking habits, and stratified by sex.
Article Synopsis
- The study assessed how different dimensions of the quantitative job-exposure matrix (SYN-JEM) impact the correlation between silica exposure and lung cancer risk, using data from 16,901 lung cancer cases and 20,965 controls from global studies.
- The analysis revealed that including all dimensions of SYN-JEM resulted in the best fit for predicting lung cancer odds, while omitting job-specific estimates led to a poor model fit.
- The findings suggest that to accurately model the exposure-response relationship between silica and lung cancer, it’s crucial to use all relevant factors, including job specifics, time, and region in the analysis.
Background: While much research has been done to identify individual workplace lung carcinogens, little is known about joint effects on risk when workers are exposed to multiple agents.
Objectives: We investigated the pairwise joint effects of occupational exposures to asbestos, respirable crystalline silica, metals (i.e.
Occupational Benzene Exposure and Lung Cancer Risk: A Pooled Analysis of 14 Case-Control Studies.
Am J Respir Crit Care Med
January 2024
Benzene has been classified as carcinogenic to humans, but there is limited evidence linking benzene exposure to lung cancer. We aimed to examine the relationship between occupational benzene exposure and lung cancer. Subjects from 14 case-control studies across Europe and Canada were pooled.
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- A study tested 40 participants (20 men and 20 women) on the discomfort caused by different masks (surgical, community, FFP2, and no mask) while performing physical tasks.
- Participants reported increased feelings of heat, humidity, and difficulty breathing as they exerted themselves and wore masks longer, especially with the FFP2 mask.
- Despite the discomfort from mask use, there was no significant impact on cognitive performance; those who struggled with discomfort reported feeling more impaired during physical activities.