Publications by authors named "B Kayhan"

Article Synopsis
  • * Out of 57 patients analyzed, significant clinical differences were observed between the treatment and untreated groups, but both groups had similar baseline demographic and laboratory characteristics.
  • * The results indicated that while early antiviral therapy led to better short-term HBsAg seroclearance rates, it did not prevent chronic hepatitis B or significantly differ in key clinical outcomes, suggesting the need for further, larger randomized studies.
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Diving is an intense physical activity under hyperbaric and hyperoxic conditions. The aim of this study is to evaluate the long-term effects of diving on the thicknesses of retinal layers and retinal anatomy in professional deep and scuba divers. The study included 52 eyes of deep divers who dive to depths of more than 130 feet (ft), 49 eyes of scuba divers who dive up to 130 ft, and 66 eyes of the control group, consisting of nondiving but regularly exercising males.

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Purpose: To investigate the reasons for the removal and/or exchange of posterior chamber phakic intraocular lenses (PCPIOLs) and the outcomes of these procedures.

Methods: In this retrospective study, PCPIOL implantations performed between January 2015 and June 2023 in a single center were reviewed. The study group consisted of the files of eyes with removed and/or exchanged PCPIOL.

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Article Synopsis
  • Causal mediation analysis helps identify how specific mediators influence the relationship between an exposure (like a genetic factor or smoking) and an outcome (like lung function), especially in complex datasets such as omics or imaging.
  • * The new PS5 framework addresses challenges in high-dimensional data by performing global mediation tests and accurately selecting and prioritizing mediators while maintaining correct causal assumptions.
  • * When applied to an imaging genetics dataset in COPD patients, PS5 revealed a significant mediation effect in the right lung's lower lobe, indicating it could be a target for treatments to lessen COPD severity related to genetic and smoking factors.
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The relationship between damage to the liver and spleen by aging and the immune response status in these two organs, which are anatomically and immunologically interconnected, is unknown. The authors investigated the histopathological, ultrastructural, and immunological effects of aging in young and aged fibrotic mice by using an experimental model. Four groups were planned, with 10 mice in each experimental group.

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