Complete genome sequences of mycobacteriophages JayJay and Rinkes.

The complete genome sequences were determined for two mycobacteriophages isolated from mc155. JayJay, a bacteriophage from cluster C1, encodes 234 putative genes, 32 tRNAs, and 1 tmRNA. Rinkes, a bacteriophage from cluster B9, harbors a smaller genome encoding 93 putative genes.

Antitubercular Activity of 7-Methyljuglone-Loaded Poly-(Lactide Co-Glycolide) Nanoparticles.

Background/objectives: Loading of natural products into poly-(lactide-co-glycolic) acid (PLGA) nanoparticles as drug delivery systems for the treatment of diseases, such as tuberculosis (TB), has been widely explored. The current study investigated the use of PLGA nanoparticles with 7-methyljuglone (7-MJ), an active pure compound, isolated from the roots of A. DC.

Complete genome sequences of mycobacteriophages Ashwin from cluster O and Chanagan from cluster A1.

Ashwin and Chanagan are double-stranded mycobacteriophages isolated from a single soil sample from a lavender flowerpot in Johannesburg, South Africa. Both are capable of infecting and lyzing and are predicted to contain 122 and 91 open reading frames, respectively, most without known function.

Complete genome sequence of Wildflower, an O cluster mycobacteriophage.

Wildflower is a cluster O mycobacteriophage with a siphoviral morphotype that displays lytic activity in . It was isolated from soil in Johannesburg, South Africa. The double-stranded genome consists of 69,364 base pairs with a GC content of 65.

Collaborative learning in the digital age: empowering tuberculosis researchers through virtual training.

Integrating whole genome sequencing (WGS) of the complex into routine care, surveillance, and research in high tuberculosis burden settings remains challenging due to limited resources and skills. While technological platforms for scaling WGS are emerging, scaling wet lab and analytic components often depends on partnerships where such skills have been established. To address this, a virtual training program was developed.