Publications by authors named "B KIRBY"
European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment.
J Eur Acad Dermatol Venereol
December 2024
Introduction: This second part of the S2k guidelines is an update of the 2015 S1 European guidelines.
Objective: These guidelines aim to provide an accepted decision aid for the selection, implementation and assessment of appropriate and sufficient therapy for patients with hidradenitis suppurativa/acne inversa (HS).
Methods: The chapters have been selected after a Delphi procedure among the experts/authors.
Introduction: Limited health literacy - the ability to access, process, and use health information and services - contributes to persistent health inequities. Yet little is known about associations of limited health literacy with impacts from the COVID-19 pandemic, particularly for US adults in rural areas. This study sought to determine associations of limited health literacy with impacts from the COVID-19 pandemic among a diverse sample of adults in rural Northern Arizona.
View Article and Find Full Text PDFArticle Synopsis
- Inactivation of the 24-hydroxylase enzyme (CYP24A1) in mice led to increased levels of calcitriol, resulting in higher intestinal calcium absorption and mild to severe hypercalcemia during pregnancy and lactation.
- Both wild-type and Cyp24a1 null mice saw similar increases in bone mineral content during late pregnancy, but Cyp24a1 nulls had significantly higher calcitriol and intestinal calcium absorption, with some null dams experiencing late gestational mortality.
- Despite some negative effects, Cyp24a1 nulls showed reduced bone loss during lactation compared to wild-types, highlighting the need for treatment options that target calcitriol levels in
Article Synopsis
- - The EXACT trial, sponsored by the National Cancer Institute, aims to evaluate whether 150 minutes of weekly moderate-intensity aerobic exercise can lower systemic inflammation in stage I-III colorectal cancer survivors compared to a control group over 12 weeks.
- - Recruitment for the study involved inviting over 3,000 survivors, with 89 screened and 60 randomized, revealing that younger age, female sex, and certain racial and clinical factors positively influenced participation.
- - Findings showed high exercise adherence at 92.2%, with all participants meeting the 80% adherence goal, and the trial will provide insights into how exercise may help prevent cancer recurrence and improve survival rates.