Associations between social-network characteristics and postpartum health behaviors and weight among a sample of women who were overweight/obese pre-pregnancy.

Background: Retention of weight postpartum increases risk for long-term morbidity, including cardiometabolic disease. Although retained weight postpartum is a complex problem, interventions generally address individual diet and activity behaviors.

Objectives: We investigated the impact of social-network factors on postpartum health behaviors and weight.

Transposon mutagenesis identifies acid resistance and biofilm genes as Shigella sonnei virulence factors in Caenorhabditis elegans infection.

Identifying essential genes in bacterial pathogens during infection can enhance knowledge and provide novel targets for antimicrobial agents' development. Currently, only Shigella flexneri essential genes during in vitro growth have been experimentally identified. This study used transposon insertion sequencing (TIS) to identify Shigella sonnei essential genes during Caenorhabditis elegans infection.

Sex-related pathophysiological mechanisms may be present before symptoms of HFpEF develop.

Aims: Understanding sex-related cardiovascular differences in those with pre-HFpEF (asymptomatic with normal ejection fraction, elevated natriuretic peptides and structural or functional heart disease) could help explain why females are more likely to develop symptomatic HFpEF compared with males. This study analyses sex-related cardiovascular differences in pre-HFpEF, including measures of cardiovascular stiffness and vascular resistance derived from cardiac magnetic resonance imaging (CMR) and Doppler echocardiography.

Methods And Results: This post hoc analysis of the PARABLE trial enrolled 250 patients with pre-HFpEF.

Exercise Habits and Preferences of Community-Dwelling Older Adults with Chronic Pain: An Exploratory Study.

Introduction: This study explored the exercise habits of community-dwelling older adults with chronic pain, examining the relationship between pain, physical activity, daily life impacts, and psychological effects.

Method: The study was conducted through a cross-sectional approach and semi-structured interviews with five participants aged fifty and above.

Result: The findings revealed that exercise participation among those with chronic pain was significantly lower than in the non-pain participants, particularly for those exercising more than three times weekly ( = 0.