New 1,3,4‒oxadiazole Quinazolines as Potential Anticancer Agents: Design, Synthesis, Biological Evaluation, and Studies.

Background: A novel series of 1,3,4‒oxadiazole connected to derivatives of quinazolinone (7a-e and 8a-f) was synthesized in the current investigation, and its anticancer and Topoisomerase‒ II inhibitory activity was evaluated.

Objective: These findings inspired the design, synthesis, and biological analysis of these 1,3,4‒oxadiazole-quinazolinone analogues as antiproliferative Topo‒II inhibitors.

Methods: The novel compound structures were determined using mass spectrometry and spectral methods (IR, NMR: H & C).

Biodiesel production and optimization from Calophyllum inophyllum linn oil (honne oil)--a three stage method.

The present work examines the production of a biodiesel from a non-edible oil namely honne oil (Calophyllum inophyllum linn). A three stage process viz., pre-treatment, alkali catalyzed transesterification and post treatment adopted for the production is discussed.