Publications by authors named "B K So"
Reactive oxygen species (ROS)-mediated damage to macromolecules and cellular organelles is one of the major causes of senescence. Therapeutic strategies that lower ROS levels have been proposed as important treatments for senescence, but effective mechanisms for reducing ROS levels have not been discovered. Here, we aimed to find a combination that has a synergistic effect on ROS reduction using senomorphics known to reduce ROS.
View Article and Find Full Text PDFL. cultivar Dangjo (DJ), developed as a novel crop, possesses potential health benefits, such as reducing blood glucose levels. DJ contains flavonoid glycosides, bioactive compounds that have been found in various plants and have promising pharmacological effects.
View Article and Find Full Text PDFAcute effect of resistive aquatic high-intensity interval training on metabolic costs in adults.
Front Sports Act Living
October 2024
Article Synopsis
- The study aimed to explore the metabolic responses and perceived effort of young healthy adults engaged in Aquatic High-Intensity Interval Training (AHIIT) versus resistive AHIIT in a single session.
- Results showed significant changes in resting energy expenditure and perceived exertion in the resistive AHIIT group, but no notable differences in heart rate or oxygen consumption between the two training methods.
- The conclusion suggests that both AHIIT and resistive AHIIT yield similar metabolic benefits, allowing for tailored training prescriptions.
The patho-mechanism of apolipoprotein variant, APOE4, the strongest genetic risk for late-onset Alzheimer's disease (AD) and longevity, remains unclear. APOE's neighboring gene, TOMM40 (mitochondria protein transport channel), is associated with brain trauma outcome and aging-related cognitive decline, however its role in AD APOE4-independently is controversial. We report that TOMM40 is prone to transcription readthrough into APOE that can generate spliced TOMM40-APOE mRNA chimera (termed T9A2) detected in human neurons and other cells and tissues.
View Article and Find Full Text PDFArticle Synopsis
- Urinary and vascular catheters are frequently used in healthcare but are prone to infections due to biofilm formation on their surfaces, contributing to healthcare-associated infections.
- Traditional infection prevention methods like antimicrobials have limited effectiveness and are complicated by increasing antimicrobial resistance.
- This review assesses the weaknesses of current prevention strategies and explores new, uncommercialized alternatives based on the stages of biofilm formation, aiming to identify better technologies for preventing catheter-related infections in the future.