Common 8q24 sequence variations are associated with Asian Indian advanced prostate cancer risk.

Three sequence variations (rs1447295, rs16901979, and rs6983267) on 8q24 were recently shown to independently affect prostate cancer risk. Asian Indians have a low prostate cancer risk; however, in the absence of screening practices for the disease, most are diagnosed with metastatic prostate cancer. We evaluated the association of these single nucleotide polymorphisms (SNP) with advanced prostate cancer in 153 prostate cancer cases and 227 age-matched controls (northern India).

Analysis of the RNASEL/HPC1, and macrophage scavenger receptor 1 in Asian-Indian advanced prostate cancer.

Objectives: Prostate cancer (PC) varies widely by geographic location and ethnicity. American men have a high PC risk but most have localized disease. In contrast, Asian Indians have a low PC risk but most are diagnosed with metastatic disease.

Antagonistic activity of Lactobacillus acidophilus fermented milk against different pathogenic bacteria.

Lactobacillus acidophilus strains tested showed inhibitory activity towards Salmonella typhi, Staphylococcus aureus, Escherichia coli, Proteus vulgaris and Yersinia enterocolitica. However, wide variations in the activity of the strains were observed. Antagonistic activity of the strains exhibited high heat stability (120 min at 92 degrees C, 15 min at 121 degrees C) but it was markedly influenced by changes in pH.

Characterization of Lactobacillus acidophilus strains for use as dietary adjunct.

Seven Lactobacillus acidophilus strains were studied for their morphology, biochemical properties, growth behaviour, bile tolerance, cholesterol uptake and survival at low pH. The strains significantly differed in their biochemical and beneficial traits. The strains which exhibited cholesterol uptake and ability to grow in the presence of 0.

Antibiotic sensitivity pattern of various Lactobacillus acidophilus strains.

Seven L. acidophilus strains were examined for their antibiotic sensitivity against various chemotherapeutic agents and all of them were found to be sensitive to novobicin, chloramphenicol, ampicillin, erythromycin, oxytetracycline and chlorotetracycline, whereas, all were resistant to norfloxacin and nalidixic acid. The sensitivity towards remaining antibiotics varied among the strains.