Publications by authors named "B K Chopra"
Formulation, Development and Evaluation of Effervescent Tablet of Green Tea (Camellia sinensis).
Cent Nerv Syst Agents Med Chem
February 2025
Background: Camellia sinensis has an extensive variety of pharmacological properties, including neuroprotection, photo-aging resistance, stress resistance, antioxidant, anti-tumour, hypoglycemic, antibacterial, and antiviral effects tracing a good potential in addressing illness and preventing disease. Challenges with conventional dosage forms include patient incompatibility, improper dosing, the inclusion of microplastics, etc. Objective: The present work aims to deliver a novel formulation devoid of microplastics and with improved consumer compliance.
View Article and Find Full Text PDFCalcineurin inhibitors have been the choice for maintenance immunosuppression (IS) in kidney transplant recipients (KTR), but they are associated with nephrotoxicity and metabolic side effects. We aim to compare the long-term outcomes of KTR on belatacept (bela) versus tacrolimus (tac) IS, in all KTRs and various subgroups. Using the UNOS-STAR files, we identified adult first-KTR from 2010 to 2022.
View Article and Find Full Text PDFHarnessing Therapeutic Potential of Allicin Against Cancer: An Exploratory Review.
Anticancer Agents Med Chem
January 2025
Background: The biological name of garlic is Allium sativum L., a familiar spice with various health benefits. These benefits are mainly attributable to the compound diversity of garlic, which includes saponins, polysaccharides, organic sulfides, and phenolic compounds.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigated the impact of prolonged cold ischemia times (CIT) and donor age on kidney transplant outcomes for recipients of kidneys from donors after circulatory death (DCD), utilizing a large dataset from 2010-2024.
- - Analysis of 4092 mate-kidney pairs showed no significant differences in patient death or allograft failure between kidneys with CITs greater than 24 hours and those with shorter CITs.
- - Prolonged CITs were linked to a higher likelihood of delayed graft function (DGF), suggesting that accepting kidneys with longer CITs should still be considered despite the associated risks.
Background: The role of steroid maintenance (SM) therapy in older adults with kidney retransplants is uncertain due to the intricate balance between rejection and adverse event risks. We aimed to assess their long-term outcomes, comparing SM versus early steroid withdrawal (ESW).
Methods: Retrospective United Network for Organ Sharing registry cohort study.