Applied photosynthesis: An idea whose time has come.

Advancements in materials science, synthetic biology, and nanomaterial engineering are revolutionizing renewable energy technologies, creating new pathways for sustainable energy production. Biohybrid devices-systems combining biological components with engineered synthetic materials-are emerging as powerful platforms for harnessing solar energy to drive hydrogen production, photovoltaics, catalysis, and biosensing. This collection of articles presents leading-edge research in biohybrid energy systems, where photosynthetic mechanisms are redeployed to develop eco-friendly, high-efficiency alternatives to conventional solar technologies.

In vitro photocurrents from spinach thylakoids following Mn depletion and Mn-cluster reconstitution.

Biohybrid devices that generate an electrical signal under the influence of light due to photochemical reactions in photosynthetic pigment-protein complexes have many prospects. On the one hand, the oxygen-evolving complex of photosystem II allows the use of ubiquitous water as a source of electrons for photoinduced electron transfer in such devices; on the other hand, it is the most vulnerable part of the photosynthetic apparatus. From the perspective of sustainable operation of bio-based hybrid devices, it is helpful to analyze how removing or modifying the Mn cluster will affect the performance of the bio-hybrid device.

Factors Associated with Medical Care-Seeking and Stool Sample Submission for Diarrheal Illness, FoodNet, United States, 2018-2019.

Laboratory-based surveillance for enteric pathogens causing diarrhea is foundational for monitoring foodborne diseases in the United States. However, diarrheal illnesses are not always confirmed by laboratory testing, so estimates of the true number of illnesses must adjust for underdiagnosis, including underdiagnosis due to ill persons not seeking medical care or submitting a stool sample for laboratory testing. We assessed these factors among persons with an acute diarrheal illness who responded to the most recent Foodborne Diseases Active Surveillance Network (FoodNet) Population Survey (2018-2019).

Factors associated with vision loss in idiopathic intracranial hypertension patients with severe papilledema.

Background/objectives: Our aim was to compare factors associated with poor versus good visual outcomes in idiopathic intracranial hypertension (IIH) patients with severe papilledema at initial presentation.

Subjects/methods: Retrospective review of consecutive IIH patients (1/1/2013-6/10/2023) with severe papilledema (Frisén grade 4-5 and/or atrophy in at least one eye); Patients were divided into "poor visual outcome" (poor visual acuity and constricted visual field in at least one eye) and "good visual outcome" (good visual acuity and only mild visual field changes in both eyes) at >6 months for medically-treated patients and >3 months follow-up for surgically-treated patients.

Results: We included 134 IIH patients with severe papilledema (70 had poor and 64 had good visual outcomes).