CD30-positive lymphoproliferative disorders are a group of diseases which represent the second most common (30 percent) subgroup of cutaneous T-cell lymphomas. They present a challenging diagnosis given their similar findings histologically and clinically in comparison to other cutaneous pathologies. Use of immunohistochemical staining to identify CD30 positivity facilitates a more rapid development of the appropriate management plan.
View Article and Find Full Text PDFWe describe a case of an 85-year-old Caucasian female who presented to the dermatology clinic with pruritic, scaly hyperpigmented papules and plaques with surrounding erythema in the left axilla. Based on the history and physical examination, there was concern for possible varicella zoster infection, and the patient was started on valacyclovir 1000 mg three times daily for seven days. A shave biopsy was taken from the left axilla to confirm a diagnosis.
View Article and Find Full Text PDFLupus erythematosus (LE) is a complex autoimmune disease that presents with a wide variety of clinical and immunopathological features, making it challenging to reach a correct and prompt diagnosis. Patients with LE most frequently present with cutaneous and rheumatologic manifestations. As cutaneous findings may be the first sign of disease, their timely recognition is important for proper workup and management of LE.
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