Publications by authors named "B Jamard"
Objectives: To compare two strategies-a hydrocortisone replacement strategy and a prednisone tapering strategy-for their success in glucocorticoid discontinuation in patients with rheumatoid arthritis (RA) with low disease activity (LDA).
Methods: The Strategies for glucocorticoid TApering in Rheumatoid arthritis (STAR) study was a double- blind, double-placebo randomised controlled trial including patients with RA receiving a stable dose of glucocorticoid 5 mg/day for ≥3 months and were in LDA for ≥3 months. Patients were randomly assigned in a 1:1 ratio to either replace prednisone with 20 mg/day of hydrocortisone for 3 months, then reduce to 10 mg/day for 3 months before discontinuation or to taper prednisone by 1 mg/day every month until complete discontinuation, contingent on maintaining LDA.
Article Synopsis
- A study compared two methods for stopping glucocorticoids in rheumatoid arthritis patients with low disease activity: replacing prednisone with hydrocortisone or tapering prednisone down gradually.
- The trial included 102 patients and found that after 12 months, 55% in the hydrocortisone group and 47% in the tapering group successfully discontinued glucocorticoids, showing no significant difference between the groups.
- The results indicated that neither strategy was superior for achieving discontinuation, and there were no serious side effects related to adrenal insufficiency observed.
Objectives: Tropheryma whipplei infection can manifest as inflammatory joint symptoms, which can lead to misdiagnosis of inflammatory rheumatic disease and the use of disease-modifying antirheumatic drugs. We investigated the impact of diagnosis and treatment of Tropheryma whipplei infection in patients with inflammatory rheumatic disease.
Methods: We initiated a registry including patients with disease-modifying antirheumatic drugs-treated inflammatory rheumatic disease who were subsequently diagnosed with Tropheryma whipplei infection.
Article Synopsis
- - The study aimed to evaluate cardiovascular risk factors and events in patients with psoriatic arthritis (PsA) compared to a control group, focusing on how adjustments to cardiovascular risk equations affect these comparisons and the percentage of patients who meet LDL cholesterol targets.
- - Using data from 207 PsA patients and 414 controls, the results showed that PsA patients had higher prevalence rates of cardiovascular risk factors and events, particularly after factoring in age and gender, leading to an increased risk as measured by modified risk scoring equations.
- - Despite the higher risk percentages observed in the PsA group when using adjusted scoring methods, the overall percentages of high LDL cholesterol levels between PsA patients and controls did not significantly differ, although there was a slight
Background: To search for association between ultrasound (US) enthesis abnormalities and disease activity, spine and sacro-iliac joints (SIJ) MRI inflammatory lesions and spine structural changes in a cohort of patients suspected for axial spondyloarthritis (SpA).
Methods: Of 708 patients included in the DESIR(Devenir des Spondyloarthrites Indifférenciées Récentes) cohort, 402 had an US enthesis assessment and were selected for this study. Achilles, lateral epicondyles, superior patellar ligament, inferior patellar ligament entheses were systematically US scanned and abnormalities were summed in US structural and power Doppler (PDUS) scores.