Nursing research in the hospital and beyond.

Outside is conceptualized as (1) settings in a larger system of care and (2) ways in which nursing transcends roles and relationships traditionally found in hospitals. The hospitals is one of many settings in the continuum of care. Although episodic hospitalization may be required, the health experience involves interface with sites outside the hospital.

Evaluation of laser dye mutagenicity using the Ames/Salmonella microsome test.

Twenty-five laser dyes and four analogs were tested for mutagenicity in the Ames/Salmonella test. Seven dyes and two analogs gave positive mutagenic responses with bacterial strains TA1538 and TA98. Of two widely used families of laser dyes (coumarins and rhodamines), four coumarin samples, but none of the rhodamine samples, were mutagenic.

Isolation and characterization of new mutagens from fried ground beef.

Frying of ground beef at 250 degrees C results in the formation of a series of mutagenic heterocyclic amines, possibly as many as 10 distinct compounds. In this study, the mutagens are separated by aqueous/acid extraction from the beef, XAD adsorption, acid/neutral/base-liquid/liquid extraction, preparative reverse phase h.p.