Publications by authors named "B J Tonge"
Background: Few studies have explored community participation for autistic adults, with or without intellectual disability. This study aims to investigate how autistic adults participate in the community, and the childhood and adulthood factors that predict community participation in adulthood.
Method: Eighty-four autistic adults (mean age 34 years; 67% with co-occurring intellectual disability) initially recruited as children and adolescents, participated in the current study.
Article Synopsis
- The study aimed to create a prioritized list of research themes and essential data points related to mental health issues in children and adolescents presenting to emergency departments (ED).
- A Delphi survey involving various stakeholders, including clinicians and patients, was conducted to gather and prioritize these research themes and data points.
- The final results highlighted 71 key items, focusing on safety in the ED, the effectiveness of mental health spaces, follow-up care, and important data like risk factors and behavioral disturbances.
Article Synopsis
- Prenatal exposure to bisphenol A (BPA) is linked to increased autism symptoms and diagnosis in young boys with low aromatase gene activity.
- Research indicates that high BPA levels impact brain methylation patterns related to aromatase, which may mediate the risk of autism.
- Male mice studies suggest that mid-gestation BPA exposure causes ASD-like behaviors, but these can be improved with the intervention of 10-hydroxy-2-decenoic acid (10HDA).
Background: Existing clinical trials of cognitive behavioural therapies with a trauma focus (CBTs-TF) are underpowered to examine key variables that might moderate treatment effects. We aimed to determine the efficacy of CBTs-TF for young people, relative to passive and active control conditions, and elucidate putative individual-level and treatment-level moderators.
Methods: This was an individual participant data meta-analysis of published and unpublished randomised studies in young people aged 6-18 years exposed to trauma.
Introduction: Children and adolescents are increasingly prescribed antipsychotic medications off-label in the treatment of behavioural disorders. While antipsychotic medications are effective in managing behavioural issues, they carry a significant risk of adverse events that compromise ongoing physical health. Of particular concern is the negative impact antipsychotic medications have on cardiometabolic health.
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