The role of meal timing in appetitive responses to acute exercise in adolescents with and without obesity: A systematic review and meta-analysis.

Physical activity has been shown to improve various aspects of metabolic health and is frequently applied as an intervention in the management and prevention of overweight/obesity. Chrono-exercise can be studied in relation to time of day and timing in relation to a meal, which encompasses chronology and duration of the temporal interval, but the latter has received limited attention to date. This brief review and meta-analysis investigates whether the timing of a meal subsequent to acute exercise, in children and adolescents with and without overweight/obesity, moderates eating behaviour and appetite.

Automated segmentation of deep brain structures from Inversion-Recovery MRI.

Methods for the automated segmentation of brain structures are a major subject of medical research. The small structures of the deep brain have received scant attention, notably for lack of manual delineations by medical experts. In this study, we assessed an automated segmentation of a novel clinical dataset containing White Matter Attenuated Inversion-Recovery (WAIR) MRI images and five manually segmented structures (substantia nigra (SN), subthalamic nucleus (STN), red nucleus (RN), mammillary body (MB) and mammillothalamic fascicle (MT-fa)) in 53 patients with severe Parkinson's disease.

Genetic characterization of paternal lineages by Y-STR in three sample populations in Northeastern Brazil.

Genetic markers of the Y chromosome are powerful tools for investigating paternal ancestry and are widely used in population and forensic genetics. However, in order to obtain statistics with a higher degree of certainty using these markers, it is necessary to obtain haplotypic frequencies from a representative database, as well as knowing the diversity and structure of the population. The aim of this study was to investigate the genetic diversity of a sample of 1114 unrelated men from three states in the Northeast of Brazil: Paraíba, Pernambuco and Ceará, through the analysis of 23 Y-STRs and to contribute to the expansion of the Brazilian database on these markers.

Dissemination of arr-2 and arr-3 is associated with class 1 integrons in Klebsiella pneumoniae clinical isolates from Portugal.

\nKlebsiella pneumoniae is a common pathogen of healthcare-associated infections expressing a plethora of antimicrobial resistance loci, including ADP-ribosyltransferase coding genes (arr), able to mediate rifampicin resistance. The latter has activity against a broad range of microorganisms by inhibiting DNA-dependent RNA polymerases. This study aims to characterise the arr distribution and genetic context in 138 clinical isolates of K.

Clinical Benefits of Parasternal Block with Multihole Catheters when Inserted before Sternotomy.

Background: The aim of this study was to assess whether parasternal block with multihole catheters inserted before surgical incision enables to alleviate postoperative analgesia and opioid reduction in cardiac surgery patients with sternotomy.

Methods: Twenty-six adult patients scheduled for cardiac surgery with sternotomy aged between 18 and 84 olds were included in this prospective, monocentric, open, single-group trial. Two parasternal multihole catheters were inserted on each side of the sternum before the surgical skin incision for cardiac surgery and 10 mL of ropivacaine 7.