Publications by authors named "B J Nelson"
Background: An elevated startle reflex in anticipation of unpredictable threat has been associated with concurrent anxiety disorders. However, only one study to date has examined whether startle potentiation in anticipation of unpredictable threat predicts the development of anxiety disorders.
Method: In a community sample of 309 adolescents, we examined whether the startle reflex in anticipation of predictable or unpredictable threat at age 15 predicted onset of generalized anxiety disorder (GAD) and social anxiety disorder (SAD) at age 18.
Article Synopsis
- Individuals at ultra-high risk (UHR) for psychosis with persistent attenuated psychotic symptoms (APS) show worse clinical and functional outcomes compared to those who remit, closely resembling individuals who transition to psychosis.
- After an initial period, the symptom and functioning trajectories for those with persistent APS diverge quickly from those who remit.
- Prediction of non-remission improves significantly with longitudinal data (6-month follow-up) rather than relying on baseline data alone, indicating the need for consistent monitoring and intervention for UHR individuals with persistent APS.
Background: There are limited evidence-based guidelines to predict which osteochondritis dissecans (OCD) lesions will heal with nonoperative treatment.
Purpose: To train a set of classification algorithms to predict nonoperative OCD healing while identifying new clinically meaningful predictors.
Study Design: Case-control study; Level of evidence, 3.
The startle eyeblink reflex is thought to function as a means of orienting to salient stimuli, and, by proxy, sensitivity to threat cues. The absence or attenuation of this reflex may thus suggest disengagement from one's environment, potentially in circumstances when engagement is called for, and, therefore, may serve as a potential marker for dissociation as it occurs. The present study investigates whether individual differences in startle response magnitude and habituation are attributable to early and multiple trauma exposure, dissociation, and PTSD symptom severity.
View Article and Find Full Text PDFCurrently available animal models for calcium oxalate kidney stones are limited in their translational potential. Particularly with increasing interest in gut microbiota involvement in kidney stone disease, there are limited animal models which can be used. As such, we have developed a novel diet-induced hyperoxaluria murine model which addresses some of the shortcomings of other currently available models.
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