Background: To determine if face, head, or neck burns increases risk of persistent sleep disordered breathing (SDB) or obstructive sleep apnea (OSA) after adenotonsillectomy.
Methods: The TriNetX database was used to gather data for patients who had face, head, or neck burn including mouth and pharynx and history of sleep study with adenotonsillectomy. A comparison of persistent SDB or OSA was done between cohort 1, a group with sleep study and adenotonsillectomy after burn injury, and cohort 2, a group with treatment before a burn.
To examine the accuracy, engagement, and quality of otolaryngology-related educational videos produced by health care providers on Instagram. A systematic search on Instagram was conducted to identify the top 150 video posts using the hashtags #Otolaryngology, #Otolaryngologist, and #ENTeducation, ranging from September 2020 to January 2024. Posts not related to otolaryngology medical education were excluded from analysis.
View Article and Find Full Text PDFEndometriosis is a common gynecologic condition that causes chronic life-altering symptoms including pain, infertility, and elevated cancer risk. There is an urgent need for new non-hormonal targeted therapeutics to treat endometriosis, but until very recently, the cellular and molecular signatures of endometriotic lesions were undefined, severely hindering the development of clinical advances. Integrating inherited risk data from analyses of >450,000 individuals with ∼350,000 single cell transcriptomes from 21 patients, we uncover M2-macrophages as candidate drivers of disease susceptibility, and nominate IL1 signaling as a central hub impacted by germline genetic variation associated with endometriosis.
View Article and Find Full Text PDF