Publications by authors named "B J M Hofman"
Article Synopsis
- - Atherosclerotic cardiovascular disease (ACD) is a major cause of death globally, with permanent stent implants being the standard treatment despite potential complications like thrombus formation and stent fracture that can affect long-term safety and effectiveness.
- - Biodegradable metals, particularly Molybdenum (Mo), have emerged as promising alternatives for stent implants due to their favorable healing responses and minimal adverse effects, although concerns about high-dose toxicity remain.
- - This review will examine the biochemical role of Mo in cardiovascular health, its benefits over other biodegradable metals, and the current limitations of research, ultimately aiming to translate these findings into practical clinical applications.
Ubiquitin-specific proteases (USPs) are the main members of deubiquitinases (DUBs) that catalyze removing ubiquitin chains from target proteins, thereby modulating their half-life and function. Enzymatic activity of USP21 regulates protein degradation which is critical for maintaining cell homeostasis. USP21 determines the stability of oncogenic proteins and therefore is implicated in carcinogenesis.
View Article and Find Full Text PDFArticle Synopsis
- The Letter reports the most accurate measurement so far of the matter-antimatter imbalance during Pb-Pb collisions at a high energy level of 5.02 TeV.
- It utilizes the Statistical Hadronization framework to determine precise values for the electric charge and baryon chemical potentials, μ_{Q} and μ_{B}.
- The analysis of antiparticle-to-particle yield ratios shows that the collisions create a system that is generally baryon-free and electrically neutral at midrapidity.
The ALICE Collaboration reports the measurement of semi-inclusive distributions of charged-particle jets recoiling from a high transverse momentum (high p_{T}) hadron trigger in proton-proton and central Pb-Pb collisions at sqrt[s_{NN}]=5.02 TeV. A data-driven statistical method is used to mitigate the large uncorrelated background in central Pb-Pb collisions.
View Article and Find Full Text PDFK^{+}K^{-} pairs may be produced in photonuclear collisions, either from the decays of photoproduced ϕ(1020) mesons or directly as nonresonant K^{+}K^{-} pairs. Measurements of K^{+}K^{-} photoproduction probe the couplings between the ϕ(1020) and charged kaons with photons and nuclear targets. The kaon-proton scattering occurs at energies far above those available elsewhere.
View Article and Find Full Text PDF