Perioperative chemotherapy in the treatment of osteosarcoma: a 26-year single institution review.

Background: Chemotherapy in the multimodality treatment of osteosarcoma has improved survival. Reported outcomes on adult patients are limited. Poor necrosis rates post neoadjuvant chemotherapy (NAC) is considered an adverse prognostic factor and attempts have been made to improve survival in this group.

Musculoskeletal oncology training during residency.

Purpose: To evaluate the efficacy of a musculoskeletal oncology training module during residency.

Methods: 24 orthopaedic residents with differing years of experience were recruited. 12 of them received musculoskeletal oncology training for 6 months.

Inter- and intra-observer variability associated with the use of the Mirels' scoring system for metastatic bone lesions.

Metastatic bone disease is increasing in association with ever-improving medical management of osteophylic malignant conditions. The precise timing of surgical intervention for secondary lesions in long bones can be difficult to determine. This paper aims to evaluate a classic scoring system.