Cost-effective adaptations increase rice production while reducing pollution under climate change.

Rice is a major source of greenhouse gas (GHG) and nitrogen pollution. While best management practices have been developed to enhance the sustainability of rice production under current climates, their adaptability and efficacy under future climate scenarios remain uncertain. Here we evaluated 49 best management practices across global grid cells of rice-producing areas in terms of increasing rice production, reducing GHG emissions and minimizing nitrogen pollution under future climate conditions.

An on-Demand Oxygen Nano-vehicle Sensitizing Protein and Nucleic Acid Drug Augment Immunotherapy.

Hypoxia severely limits the antitumor immunotherapy for breast cancer. Although efforts to alleviate tumor hypoxia and drug delivery using diverse nanostructures achieve promising results, the creation of a versatile controllable oxygen-releasing nano-platform for co-delivery with immunostimulatory molecules remains a persistent challenge. To address this problem, a versatile oxygen controllable releasing vehicle PFOB@F127@PDA (PFPNPs) is developed, which effectively co-delivered either protein drug lactate oxidase (LOX) or nucleic acids drug unmethylated cytosine-phosphate-guanine oligonucleotide (CpG ODNs).

Development of a droplet digital PCR method for the detection of .

Background: Human infection with is mainly manifested as non-gonococcal urethritis, where it can lead to cervicitis, premature rupture of membranes and abortion in women, as well as infertility in males, which becomes a major problem in clinical diagnosis and treatment. At present, real-time fluorescence quantitative PCR and culture are the two main methods for detecting UU. The real-time fluorescence quantitative PCR method is cumbersome and cannot accomplish absolute quantification on nucleic acids, while the cultivation method has limitations such as low sensitivity and being time-consuming.

Quantifying the accelerated diffusion and cost savings of global solar photovoltaic supply chains.

Solar photovoltaic (PV) is critical for achieving the 2030 global target of tripling renewable power capacity. Over the past two decades, the global supply chain has significantly reduced the cost of solar PV products enabling widespread adoption. However, many countries are now implementing decoupling measures to enhance supply chain security and boost local economies.