Developing and Assessing a Scalable Digital Health Tool for Pretest Genetic Education in Patients With Early-Onset Colorectal Cancer: Mixed Methods Design.

Background: National guidelines recommend germline genetic testing (GT) for all patients with early-onset colorectal cancer. With recent advances in targeted therapies and GT, these guidelines are expected to expand to include broader groups of patients with colorectal cancer. However, there is a shortage of genetic professionals to provide the necessary education and support for informed consent.

Thermal Characterization and Heat Capacities of Seven Polyphenols.

Polyphenolic compounds are key elements in sectors such as pharmaceutics, cosmetics and food; thus, their physicochemical characterization is a vital task. In this work, the thermal behavior of seven polyphenols (-resveratrol, -polydatin, kaempferol, quercetin, myricetin, hesperidin, and (-)-epicatechin) was investigated with DSC (differential scanning calorimetry) and TGA (thermogravimetric analysis). Melting temperatures, enthalpies of fusion and decomposition temperatures were determined, and heat capacities were measured in the temperature range from 283.

A proposal of a fecal scoring system based on physicochemical analyses of suckling pig feces.

Background: Digestive disorders are one of the main health problems in suckling piglets. The correct visual identification of feces in suckling piglets is an important tool for the diagnosis of enteric diseases. The aim of the present observational study was to analyze different physicochemical parameters of the feces of suckling piglets aged 0 to 21 days: visual appearance (color and consistency), fecal dry matter (FDM) content and pH.

Clinical Consultation in the Workplace: Are There Implications for Response Attitudes?

The clinical-organizational context (where clinical psychology services are provided in the individuals' professional setting) has still been insufficiently approached in research, namely the influence it may have on the response attitudes of individuals undergoing psychological assessment. Our main goal is to find out if, when psychological assessment occurs in the workplace context, patients being assessed present specific response bias that may have implications for the clinical results and correlative decisions. Five hundred and ten adult participants grouped in two samples of ambulatory patients - Clinical-Organizational Sample (COS = 238) and Clinical Sample (CS = 272) - were assessed with the Minnesota Multiphasic Personality Inventory-2-RF validity and substantive scales.

Extensive Leg Ulcers in a Patient With Monoclonal Gammopathy.

A 60-year-old male was admitted from the emergency department with extensive leg ulcers and polyarticular joint pain. Cryocrystalglobulinemia was diagnosed through positive cryoglobulin studies and characteristic histopathological findings. Treatment with bortezomib led to complete clinical resolution.