Hyperhomocysteinemia Causing Vascular Occlusion and Complicated by Heparin-Induced Thrombocytopenia and Gastrointestinal Bleed.

Homocysteine, an intermediate amino acid, is involved in methionine metabolism, which is crucial for various physiological pathways, including protein synthesis and DNA methylation. Elevated levels of homocysteine have been implicated as both a modifiable and unmodifiable risk factor in cardiovascular disease, influencing atherosclerotic disease formation and hypercoagulability. Mechanisms linking elevated homocysteine levels to vascular occlusion involve endothelial dysfunction, inflammation, and enhanced thrombotic potential.

Perforated Jejunal Diverticulum Mimicking Diverticulitis: A Case Report of Acute Abdominal Pain in an Elderly Patient.

Jejunal diverticulosis is a rare form of diverticulosis characterized by acquired pseudodiverticula in the small bowel. Although most cases are asymptomatic, the condition can present diagnostic challenges due to its atypical presentation. Complications such as perforation can lead to acute abdomen, significantly increasing morbidity and mortality.

Constructing community in the Neolithic of southern Jordan: Quotidian practice in communal architecture.

The emergence of food production during the earliest Neolithic of the Near East was accompanied by profound changes in the ways in which societies were organized. Elaborate and multi-stage mortuary practices involving the removal, caching, and plastering of symbolically charged skulls are thought to have played an important role in cross-cutting household lines to integrate communities and maintain social cohesion during the late tenth to ninth millennium cal BP, particularly in Middle Pre-Pottery Neolithic B settlements located in the southern Levant. While the ritual and mortuary activities associated with skull manipulation were dramatic and high impact occasions that drew people and households together, it is likely they were highly episodic and, consequently, attendant community cohesion susceptible to decay over time.