Barriers and drivers influencing people's behaviour towards COVID-19 public health and social measures in the Netherlands.

Background: The disease burden of COVID-19 infection, morbidity, and mortality was unevenly distributed across different population subgroups. A one-size-fits-all approach may not reach all groups. Identifying barriers and drivers that influence behaviour towards COVID-19 public health and social measures (PHSM) is an important step when designing tailored interventions.

Indoor carbon monoxide exposures in a retail occupancy.

In a two-story retail mall in the Southeastern United States, employees within Store A (located on the second level) began to feel headaches and general unease and discussed the symptoms among themselves. Approximately 1.5 hr later, an employee called 9-1-1.

Optimizing Ewing Sarcoma and Osteosarcoma Biopsy Acquisition: A Children's Oncology Group Bone Tumor Committee Consensus Statement.

Trends in diagnostic biopsy sample collection approaches for primary bone sarcomas have shifted in the past 2 decades. Although open/incisional biopsies used to be the predominant approach to obtain diagnostic material for Ewing sarcoma and osteosarcoma, image-guided core needle biopsies have increased in frequency and are safe for patients. These procedures are less invasive and reduce recovery times but have potential limitations.

Current Surgical Approach to Pulmonary Metastasectomy.

The lung is a common site of metastases for children and adolescents with a wide variety of solid tumors. The role for pulmonary metastasectomy is dictated by tumor histology and can serve either therapeutic or diagnostic purposes. Careful surgical planning is required to determine the optimal surgical approach and to ensure successful nodule localization.

Measuring Effectiveness Based on Patient Experience (Instead of QALYs) in US Value Assessments.

Background: A key challenge in value assessment is how to summarize effectiveness, particularly the impact of interventions on patient health-related quality of life (HRQoL). One approach is to quantify the gains in HRQoL and life expectancy together as quality-adjusted life years (QALYs); however, this approach has faced various criticisms regarding its potential discriminatory aspects toward persons with disabilities, older adults, and the most vulnerable individuals in society.

Methods: Instead of QALYs, we provide an alternative approach that summarizes HRQoL gains from the perspective of its stakeholders (e.