Publications by authors named "B J Ackerson"
This retrospective cohort study evaluated the comparative vaccine effectiveness (cVE) of licensed standard-dose cell-based versus egg-based influenza vaccines in preventing influenza hospitalization among adults 18-64 years during the 2022-2023 season. The cohort included eligible Kaiser Permanente Southern California members who received ≥ 1 dose of influenza vaccine (n = 848,334). The adjusted cVE against influenza hospitalization was -10.
View Article and Find Full Text PDFImportance: Clinical trials have demonstrated high vaccine efficacy (VE) against lower respiratory tract disease (LRTD) but enrolled a smaller proportion of persons aged 75 years or older and those with comorbidities than seen in highest-risk populations in clinical practice settings. Additionally, VE against respiratory syncytial virus (RSV)-related hospitalizations and emergency department (ED) visits is not yet fully described.
Objective: To estimate Respiratory Syncytial Virus Prefusion F (RSVpreF) effectiveness in older adults.
Article Synopsis
- A study developed and validated a natural language processing (NLP) algorithm to identify postherpetic neuralgia (PHN) from unstructured electronic health records (EHRs), aiming to improve accuracy compared to traditional diagnosis codes and prescription data.
- The research involved reviewing EHRs from a large health care system and comparing the NLP's performance with code-based methods by analyzing sensitivity, specificity, and other statistical measures.
- Results showed the NLP algorithm had high sensitivity (90.9%) and specificity (98.5%), with notable advantages in identifying PHN cases compared to code-based methods, which exhibited much lower sensitivity (52.7%-61.8%).