Validation of an Augmented Reality Based Functional Method to Determine and Render the Hip Rotation Centre During Total Hip Arthroplasty.

Background: We present a method to determine and visualise the functional centre of rotation (FCOR) of the hip during total hip arthroplasty using an augmented reality head mounted display (AR-HMD).

Methods: We developed software allowing a HoloLens to provide inside-out infrared tracking of markers affixed to cadaver femurs and 3D printed acetabuli. Two observers rotated 20 cadaver femurs twice in a matching cup, producing 80 measurements.

Development and external evaluation of a self-learning auto-segmentation model for Colorectal Cancer Liver Metastases Assessment (COALA).

Objectives: Total tumor volume (TTV) is associated with overall and recurrence-free survival in patients with colorectal cancer liver metastases (CRLM). However, the labor-intensive nature of such manual assessments has hampered the clinical adoption of TTV as an imaging biomarker. This study aimed to develop and externally evaluate a CRLM auto-segmentation model on CT scans, to facilitate the clinical adoption of TTV.

First contact(in): The complete structure of contactin 2.

In this issue of Structure, Fan et al. report the structure of the full contactin 2 ectodomain, representing the first for the contactin family. The work reveals six immunoglobulin domains are essential for intercellular interactions, explores differences in proposed contactin 2 homodimerization mechanisms, and provides an updated model for contactin 2 organization on and between cells.

Perceived Food-Related Responsibilities Among Adults Aged 60 Years and Older.

Food citizenship states individuals, organizations, and governments have responsibilities for their actions and policies around food. We conducted twenty semi-structured interviews with older adults as an exploratory study about perceived food-related responsibilities. The government and agribusiness were seen as responsible for food safety and how healthy foods are.