Publications by authors named "B Ilincic"
Chronic kidney disease (CKD) is often associated with dyslipidemia, marked by lipid abnormalities that can worsen kidney function and increase cardiovascular risk. A promising biomarker for evaluating kidney function and metabolic status in chronic kidney disease (CKD) is serum uromodulin (sUmod). This study sought to further investigate the relationship between sUmod levels and metabolic status in non-diabetic CKD patients.
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- Adipose tissue (AT) acts as a key metabolic organ and influences various bodily functions through hormonal mechanisms; this study focused on its role during COVID-19 by examining relationships between adipokines and blood cell indices in infected individuals.
- The research involved 76 COVID-19 patients and found that higher leptin levels correlated positively with body mass index (BMI) and body fat mass, while adiponectin showed an inverse relationship with BMI.
- The study also linked leptin levels to increased platelet metrics, suggesting that AT might contribute to the complex immune response during COVID-19, thus providing insights into its pathophysiology.
Article Synopsis
- - The study focused on assessing inflammatory biomarkers in patients with multiple sclerosis (MS) compared to controls, measuring levels of C reactive protein (CRP), Neutrophil-to-lymphocyte ratio (NLR), Growth differentiation factor 15 (GDF15), and neurofilaments (NFs) in serum and cerebrospinal fluid.
- - Findings indicated that MS patients exhibited lower initial levels of GDF15 and CRP compared to those with non-inflammatory CNS diseases; however, those with disease progression showed significantly higher levels of CRP and NLR after two years.
- - The results highlighted a positive correlation between CRP and both NFs and GDF15 in MS patients, suggesting that further research is necessary
Association between vitamin D hypovitaminosis and severe forms of COVID-19.
Eur Rev Med Pharmacol Sci
June 2023
Objective: Hypovitaminosis D may be associated with an increased susceptibility to infection, more severe COVID-19 forms, and a higher risk of death. The objective of this study was to investigate any possible connections between vitamin D status [as measured by serum 25-hydroxyvitamin D (25(OH)D) levels] and COVID-19 severity.
Patients And Methods: In 2021, a cross-sectional study of consecutive adult COVID-19 patients was conducted.
Background and Objectives: In chronic kidney obstruction, the severity of tubulointerstitial damage correlates best with the loss of kidney function and the risk for progression to end-stage kidney disease. The present study aimed to investigate the potential clinical significance of serum uromodulin (sUmod) as a marker of early kidney disfunction in patient with obstructive nephropathy (ON). Materials and Methods: Serum Umod level was measured by sensitive ELISA method in 57 adult patients with obstructive nephropathy and 25 healthy subjects in control group.
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