Publications by authors named "B I P Barratt"
This report is a summary of the presentations given at the European Respiratory Society's Research Seminar on Asthma Prevention. The seminar reviewed both epidemiological and mechanistic studies and concluded that; (i) reducing exposure of pregnant women and children to air pollution will reduce incident asthma, (ii) there are promising data that both fish oil and a component of raw cow's milk prevent asthma, and (iii) modulating trained immunity by either mimicking helminth infection or oral and sublingual bacterial products is a promising area of research.
View Article and Find Full Text PDFIntroduction: While associations between ambient air pollution and respiratory health in chronic obstructive pulmonary disease (COPD) patients are well studied, little is known about individuals' personal exposure to pollution and associated health effects by source.
Aim: To separate measured total personal exposure into indoor-generated and outdoor-generated pollution and use these improved metrics in health models for establishing more reliable associations with exacerbations and respiratory symptoms.
Methods: We enrolled a panel of 76 patients with COPD and continuously measured their personal exposure to particles and gaseous pollutants and location with portable monitors for 134 days on average.
Background: There is increasing evidence that air pollution and noise may have detrimental psychological impacts, but there are few studies evaluating adolescents, ground-level ozone exposure, multi-exposure models, or metrics beyond outdoor residential exposure. This study aimed to address these gaps.
Methods: Annual air pollution and traffic noise exposure at home and school were modelled for adolescents in the Greater London SCAMP cohort (N=7555).
Background: Exposure to air pollution has been associated with increased risks of cardiopulmonary diseases, cancer, and mortality, whereas residing near green spaces may reduce the risks. However, limited research explores their combined effect on oxidative stress.
Methods: A total of 251 participants with multi-time measurements were included in the longitudinal-designed study.
Article Synopsis
- - Prenatal brain development can be negatively impacted by everyday stressors and environmental pollutants, with recent advances in neuroimaging helping researchers understand these effects on brain structure and function.
- - The review highlights that both parental stress and toxicants like lead and air pollution are linked to changes in brain development, but much of the research has focused on single exposures rather than the combined effects of multiple stressors.
- - There's a call for larger cohort studies to evaluate how various concurrent exposures, including socioeconomic factors, affect fetal and neonatal brain development more comprehensively.