Publications by authors named "B Herlin"
Article Synopsis
- The assessment of epilepsy etiology focuses on identifying the epilepsy syndrome, detecting any secondary causes, and estimating seizure recurrence risk, all of which guide treatment decisions.
- Key examinations include brain MRI, ideally using a 3 Tesla machine with specific sequences to identify structural lesions, and EEG to detect abnormal electrical activity between seizures, which helps in classifying the epilepsy syndrome.
- The results from these tests must be compared with clinical data, particularly the detailed description of seizures, to ensure an accurate diagnosis and effective treatment plan.
Article Synopsis
- Diffusion MRI tractography has significantly improved our understanding of white matter pathways in the brain, particularly in studying long-range connections; however, superficial white matter bundles (SWMBs) have been less explored.
- This study investigates SWMB connectivity in humans and chimpanzees using innovative methods to classify the morphology of these bundles, utilizing anatomical atlases that detail numerous SWMBs in both species.
- Preliminary findings indicate that while familiar U-shape fibers exist in both brains, there are also complex shapes like 6 and J forms, revealing differences in SWMB localization and contributing to our understanding of brain evolution and organization.
Sex-related variability of white matter tracts in the whole HCP cohort.
Brain Struct Funct
September 2024
Behavioral differences between men and women have been studied extensively, as have differences in brain anatomy. However, most studies have focused on differences in gray matter, while white matter has been much less studied. We conducted a comprehensive study of 77 deep white matter tracts to analyze their volumetric and microstructural variability between men and women in the full Human Connectome Project (HCP) cohort of 1065 healthy individuals aged 22-35 years.
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- In medial temporal lobe epilepsy (MTLE), surgery can improve symptoms but may lead to memory decline, making it crucial to predict post-operative outcomes using fMRI tasks.
- A study of 46 MTLE patients assessed the effectiveness of fMRI language tasks in predicting memory outcomes after surgery; results showed memory fMRI had higher sensitivity in detecting hippocampal activity.
- Language fMRI, while less sensitive, provided better accuracy in predicting memory performance when hippocampal activation occurred, suggesting a need for combining both tasks to improve post-operative outcome predictions.
Article Synopsis
- Equitable access to epilepsy care varies by country, and a study in France aimed to identify factors affecting surgical access for patients with refractory medial temporal lobe epilepsy (MTLE-HS).
- The study analyzed data from 293 patients, finding that only age at onset, pensioner status, and student status significantly influenced delays in accessing video-EEG, while migratory status and socio-economic factors did not.
- The authors recommend that France enhance communication among healthcare practitioners to improve timely referrals for surgery, regardless of patients' demographics.