Improved water, sanitation, hygiene and waste services in health-care facilities, Ukraine.

Problem: Water, sanitation and waste infrastructure and services in Ukrainian health-care facilities often fail to meet global and national standards, hindering the provision of safe, quality care. The war has worsened existing problems.

Approach: To incrementally improve water, sanitation, hand hygiene, environmental cleaning and health-care waste practices, the World Health Organization (WHO) is working with the health ministry, the Ukrainian Public Health Centre and regional United States Centers for Disease Prevention and Control (CDC) to implement the Water and Sanitation for Health Facility Improvement Tool (WASH FIT).

Utilization of Participatory Research Theory and a National Framework to Advance a State Food Security Research Agenda: A Mixed-Methods Study.

The 2022 White House National Strategy on Hunger, Nutrition, and Health outlined goals for ending hunger in the US. Actions fell into five areas, called pillars; the goal of Pillar 5 was to enhance nutrition and food security research. This study leveraged participatory research theory and the National Strategy for developing a statewide, evidence-informed food security research agenda.

Real-world safety and efficacy of teclistamab in relapsed/refractory multiple myeloma: results from a multicenter, retrospective study and descriptive meta-analysis.

Patients participating in clinical trials are highly selected and may not represent the general population. The pivotal study of teclistamab (MajesTEC-1), a B-cell maturation antigen (BCMA)xCD3 bispecific antibody, demonstrated impressive response rates and progression free survival in relapsed/refractory multiple myeloma (RRMM) with acceptable toxicity. We performed a retrospective study of 58 patients treated as standard of care at four US academic centers to determine how these results translated to the real-world.

Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer's disease.

Hub regions in the brain, recognized for their roles in ensuring efficient information transfer, are vulnerable to pathological alterations in neurodegenerative conditions, including Alzheimer's disease (AD). Computational simulations and animal experiments have hinted at the theory of activity-dependent degeneration as the cause of this hub vulnerability. However, two critical issues remain unresolved.

Virtual friendly visitor program: combatting loneliness in community dwelling older adults.

Introduction: Loneliness is a critical public health issue affecting older adults, with significant impacts on their mental and physical health, including increased risks of depression, cognitive decline, and higher mortality rates, necessitating distinct approaches for each condition given their unique implications and the exacerbation of these issues during the COVID-19 pandemic. We examine the implementation and outcomes of a Friendly Visitor Program (FVP) designed to mitigate loneliness among older adults. The program involved social work student interns providing virtual visits to older adults using computers and tablets, with the goal of enhancing social interaction and support.