Publications by authors named "B Haughey"
Objectives: The prognostic significance of human papillomavirus (HPV) genotypes in oropharyngeal squamous cell carcinoma (OPSCC) has garnered considerable attention due to the increasing reliance on HPV status for clinical decision-making. This study aimed to compare the survival outcomes associated with different HPV genotypes in patients with OPSCC relative to HPV-negative tumors, providing insights into the potential implications for treatment de-intensification strategies.
Methods: Patients diagnosed with invasive OPSCC were included from the National Cancer Database (NCDB).
Safety and Postoperative Outcomes of Transoral Surgery for Oropharyngeal Carcinoma in Older Adults.
JAMA Otolaryngol Head Neck Surg
October 2024
Importance: Transoral surgery (TOS) has become the primary surgical treatment for oropharyngeal squamous cell carcinoma (OPSCC). However, despite the increasing incidence of OPSCC in older patients, data regarding the safety and postoperative outcomes of TOS in this subgroup are lacking.
Objective: This study aimed to evaluate the safety and postoperative outcomes of TOS in patients with OPSCC aged 70 years or older compared with younger individuals.
Article Synopsis
- This study investigates the role of human papillomavirus (HPV) in sinonasal squamous cell carcinoma (SNSCC), focusing on HPV testing trends and positivity rates from 2011 to 2017.
- It found that while the overall HPV positivity rate increased to 37.3%, the rate of HPV testing decreased to 45.4%, with significant variations based on demographics and geography.
- The results emphasize the need for improved testing protocols and targeted interventions, especially given the disparities observed in testing rates across different populations.
Prostaglandin E1 (PGE) is used in patients with ductal-dependent congenital heart disease (CHD). Side effects of apnea and fever are often dose dependent and occur within 48 h after initiation. We initiated a standardized approach to PGE initiation after our institution recognized a high incidence of side effects and a wide variety of starting doses of PGE.
View Article and Find Full Text PDF