Publications by authors named "B Hashemi"

Background: As a debilitating and severe repercussion, the clinical and economic impact of Status epilepticus (SE) has not been thoroughly explored in various regions around the world, especially those with limited resources. Therefore, we aimed to identify the predictors of mortality and healthcare costs associated with SE in one tertiary care center with limited resources.

Methods: This retrospective single-center cohort study, carried out at Namazi Hospital, Shiraz, Iran, included 130 SE cases from March 21, 2021, to March 20, 2022.

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Introduction: Neuropathic pain is a debilitating neurological disorder and is on the rise. Since no effective treatment has been so far approved to combat the complex pathological mechanisms behind neuropathic pain, finding new therapeutic candidates is of great importance. Astaxanthin (AST) is a carotenoid with strong antioxidant, and anti-inflammatory activities.

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Article Synopsis
  • Colorectal cancer (CRC) is a major cause of cancer deaths, but early detection can reduce mortality; traditional methods like liquid biopsies have limitations in sensitivity during early stages of CRC.
  • This study analyzes blood samples to discover new RNA biomarkers related to CRC, revealing changes in immune cell activity that occur even before cancer develops.
  • The findings highlight a potential new approach for early CRC screening using a blood test that measures 226 biomarkers linked to immune response changes during CRC progression.
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Drug hypersensitivities are common reactions due to immunologic responses. They are of utmost importance because they may generate severe and fatal outcomes. Some drugs may cause Adverse Drug Reactions (ADRs), such as drug hypersensitivity reactions (DHRs), which can occur due to the interaction of intact drugs or their metabolites with Human Leukocyte Antigens (HLAs) and T cell receptors (TCRs).

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