Dispersion of horse allergen from stables and areas with horses into homes.

Background/aim: To protect susceptible subjects from exposure to horse allergen, a Swedish national report recommended a distance of at least 500 m between homes and stables and other areas with horses. The aim of this project was to study indoor and outdoor levels of horse allergen in relation to distance from stables and horse tracks.

Methods: Indoor and outdoor samples were collected with Petri dishes at 49 sites in different housing areas and near to a track for trotting horses.

Immunoglobulin G4-antibodies to rBet v 1 and risk of sensitization and atopic disease in the child.

Background: In 1993 extremely high levels of birch-pollen were recorded in Stockholm, Sweden. This provided an opportunity to evaluate the effects of aeroallergen exposure (exp.) on the early immune response.

Dispersion of horse allergen in the ambient air, detected with sandwich ELISA.

Background: The objective was to establish an ELISA to detect horse allergen in ambient air and settled dust.

Methods: Monoclonal antibodies (mAbs) were produced against extracts of horse antigen. Two mAbs were selected and used in a sandwich ELISA.

A case of allergy to cow's milk hydrolysate.

We here report a girl, now 3 years old, who has suffered from severe food allergy since her first year of life. She was strongly allergic to cow's milk, and had high levels of IgE antibody (AB) to casein (210 kU/I), beta-lactoglobulin (43 kU/I), and alpha-lactalbumin (23 kU/l) at 12 months of age. In addition, at the same age, she showed positive (2-4+) skin prick reactions to both unboiled and boiled formulas (Profylac, Nutramigen, and Neocate), besides being positive in RAST to Nutramigen (0.

IgG subclass antibody responses to birch pollen in sibling pairs discordant for atopy.

Birch pollen allergen specific IgG and IgE antibodies were analysed in the sera of fourteen sibling pairs discordant for atopy. In addition, eight unrelated children free of atopic disease were included in the study. The presence of Bet v 1 specific antibodies in the sera were analysed by an immunoblotting assay.