Is there a benefit from routine voiding cystourethrography after ureterocystoneostomy?

Surgical repair such as ureterocystoneostomy (UCN) for vesicoureteral reflux (VUR) or primary obstructive megaureter (POM) is the treatment of choice after the failure of conservative therapy. To document the postoperative outcome, a voiding cystourethrography is routinely performed to exclude persisting reflux. Our aim was to evaluate the benefit of voiding cystoureterography (VCUG) in our patients with respect to radiation, discomfort to the child and costs.

Mesenchymal liver hamartoma in a newborn; case report.

A newborn boy had a severe, unexplained apnoea. On clinical examination a palpable abdominal mass was found extending over the right hemiabdomen. Further investigations by Ultrasound, CT scan and MRI revealed a liver tumor (7 x 5 x 9 cm).

Region- and stage-specific patterns of melanocortin receptor ontogeny in rat central nervous system, cranial nerve ganglia and sympathetic ganglia.

Observations on developmental actions of melanotropic peptides in nervous system have been difficult to interpret in the absence of data on receptor ontogeny. We investigated binding of [125I]Nle4,D-Phe7-alpha-MSH ([125I]NDP) in developing Long Evans rats from gestational day (E) 13 by quantitative autoradiography. Regional [125I]NDP binding characteristics were assessed by competition experiments in early postnatal brain.

Lichen sclerosus et atrophicus causing phimosis in boys: a prospective study with 5-year followup after complete circumcision.

We prospectively investigated 100 pediatric patients suffering from phimosis and found a 10% incidence of lichen sclerosus et atrophicus. This condition usually can be diagnosed preoperatively because of its classic manifestation of severe phimosis due to a sclerotic, whitish ring at the tip of the prepuce, which in our cases was accompanied by sclerogenous glanular lesions. To our knowledge our study represents the first evidence that the development of secondary phimosis with no apparent reason in school-age boys is highly suggestive for lichen sclerosus et atrophicus.

Is neuronal intestinal dysplasia (NID) a primary disease or a secondary phenomenon?

In order to identify possible underlying ganglion-cell disorders, specimens have been taken in neonates and infants with intestinal obstruction treated between January 1988 and June 1992. NID was confirmed in 3 patients with intestinal malformation, 2 patients with neonatal intestinal obstruction, 3 patients with meconium peritonitis, 1 patient with persistent constipation after Duhamel's pull-through for Hirschsprung's disease and 1 patient with rectal stricture after conservative treatment for necrotising enterocolitis. Additionally, NID was found in 1 patient with recurrent prolapse of an ileostomy.