An Early-Stage Economic Evaluation of Superabsorbent Wound Dressings for the Management of Moderately to Highly Exuding Leg Ulcers in Slovakian Settings.

Background: The management of chronic leg ulcers, including venous leg ulcers (VLUs), causes a considerable economic and clinical burden to healthcare systems. Factors such as nursing time, hospital care, and wound dressings account for approximately 85% of the total cost. Superabsorbent dressings (eg, superabsorbent polymers [SAPs]) are recommended as a first-line treatment for moderately to highly exuding VLUs.

The value of epidemiological data for pressure ulcer/injury management.

Pressure ulcers/injuries (PU/Is) are a burden on healthcare systems worldwide. They are costly and have a negative impact on the quality of life of patients. PU/Is cause discomfort, prolong hospital stays and can even lead to death.

Obesity induced by Borna disease virus in rats: key roles of hypothalamic fast-acting neurotransmitters and inflammatory infiltrates.

Human obesity epidemic is increasing worldwide with major adverse consequences on health. Among other possible causes, the hypothesis of an infectious contribution is worth it to be considered. Here, we report on an animal model of virus-induced obesity which might help to better understand underlying processes in human obesity.

Enthalpy friction: heat flow modelling of unexpected temperature profiles in mechanochemistry of metal-organic frameworks.

Mechanochemical reactions by ball milling are becoming increasingly popular across a wide range of chemical sciences, but understanding and evaluation of temperature during such processes remains a persistent challenge, especially for organic and metal-organic materials. Here, we describe the first methodology for precise real-time measurement of sample temperature during mechanochemical transformations. Using this technique coupled with real-time reaction monitoring by synchrotron X-ray diffraction and numerical simulations of heat flow, we have shown that the temperature profiles of mechanochemical reactions are dominantly determined by the energy dissipated through friction between the sample and the moving milling assembly, while the reaction enthalpy will usually be comparatively insignificant.