Anode free concepts are gaining traction in battery research. To improve cyclability, a better understanding of the deposition processes and morphologies is necessary. Correlative experiments enable a link between a variety of properties obtained, such as chemical, mechanical or electrochemical data.
View Article and Find Full Text PDFBackground: Digital Healthcare Solutions (DHS) are transforming healthcare by improving patients' experiences, safety and quality of care. However, despite all the proposed and observed advantages of DHS, a growing body of research suggests that these DHS are not equally accessible to all. This research aimed to assess whether equity frameworks for digital health solutions can be used to guide the development of digital health solutions to increase access to care for dementia patients in the UK and, thereafter, develop practical guidelines to guide the design of equitable DHS products to address this growing issue.
View Article and Find Full Text PDFBackground/objectives: KMT2B-related dystonia (DYT28, OMIM #617284) is a progressive neurological condition characterized by early onset movement disorders with autosomal dominant inheritance. In this study, we describe the use of a genome methylation episignature methodology to functionally validate two variants of uncertain significance (VUS) in the KMT2B gene.
Methods: Genome-wide methylation status was assessed using the EPIC methylation assay in peripheral blood samples from two subjects with early onset movement disorder and missense variants of uncertain significance in the KMT2B gene (p.
Introduction: Increasing intraspecific genetic variation (IV) has been identified as a potential factor to improve productivity and stabilise botanical composition in plant communities. In grasslands systems, this could offer a lever to manage uncertainties of production and variability in the harvested species balance. However, little is known about the conditions to favour IV impact and the mechanisms at play.
View Article and Find Full Text PDFPurpose: To assess subretinal fibrosis (SF) occurrence in neovascular age-related macular degeneration (nAMD), according to macular neovascularisation (MNV) subtypes.
Methods: A Retrospective national multi centre cohort study included eyes with naive nAMD. Main outcome measures were, according to MNV subtypes, cumulative incidence for SF, risk factors, and best corrected visual acuity (BCVA) for 36 months.