Diurnal variation of visual functions for driving with and without orthokeratology: A multicenter study.

Purpose: To investigate orthokeratology-related diurnal variations in visual acuity, contrast sensitivity, mesopic (twilight) vision, and glare sensitivity, and to verify compliance with requirements for driver licensing.

Methods: In this prospective, multicenter, controlled study, fifty myopic (range, -1.00 to -4.

Process Development and Scale-Up of a Novel Atypical DAT Inhibitor ()-CE-123.

Large-scale syntheses of small molecules and kilo laboratories are crucial steps in drug development, especially in advanced stages. ()-5-((Benzhydrylsulfinyl)methyl)thiazole, ()-CE-123, a potent, selective, and novel atypical DAT inhibitor, has undergone iterative testing as part of the preclinical evaluation step. This required the process transfer, scale-up, and synthesis of a 1 kg preclinical batch.

Alloy information helps prioritize material criticality lists.

Materials scientists employ metals and alloys that involve most of the periodic table. Nonetheless, materials scientists rarely take material criticality and reuse potential into account. In this work, we expand upon lists of "critical materials" generated by national and regional governments by showing that many materials are employed predominantly as alloying elements, which can be a deterrent to recovery and reuse at end of product life and, likely as a consequence, have low functional end-of-life recycling rates, among other problematic characteristics.

Uncertain Future of American Lithium: A Perspective until 2050.

During the 20th century, the United States went from being the largest producer and user of lithium to being heavily reliant on imports from Asia, particularly lithium-ion batteries. To explore different futures for U.S.

Validation of the R-Biopharm AG RIDASCREEN® Histamine (Enzymatic) Kit.

Background: RIDASCREEN® Histamine (enzymatic) is an enzymatic test kit for quantification of histamine in fresh fish, canned fish, fish meal, cheese, and wine.

Methods: Fish products are extracted with boiling water, while cheese is extracted with water, and the extract is treated with perchloric acid/potassium hydroxyde. Wine is extracted with the reagents of RIDA® Sample Decolorant kit to eliminate color pigments and interfering compounds.