A Possible More Precise Management Unit Delineation Based on Epigenomic Differentiation of a Long-Distance-Migratory Marine Fish Scomberomorus niphonius.

Understanding population structure and adaptive history is critical for designing appropriate management regulations for fisheries and conserving adaptive potential for the future. However, this is not easy for marine fish, especially those with long-distance migration abilities. In this study, we constructed a high-quality reference genome for Japanese Spanish mackerel (Scomberomorus niphonius) and explored its population structure using whole genomic and epigenomic data.

Hypersaline organic wastewater treatment: Biotechnological advances and engineering challenges.

The sustainable treatment of hypersaline organic wastewater (HSOW) remains a significant challenge in industrial wastewater management, as conventional approaches often fail to meet stringent discharge standards and low-carbon sustainability targets. Halotolerant and halophilic microbial strains offer promising solutions, yet their application is hindered by limited stress resistance, thus hindering effective treatment and achieving near-zero liquid discharge. In this review, we systematically examine endogenous strategies, such as microbial mutualism and genetic engineering, alongside exogenous approaches, including functional materials, electrical and magnetic stimulation, and 3D bioprinting, to improve microbial resilience in hypersaline environments.

Polystyrene nanoplastics trigger ferroptosis in Nrf2-deficient gut via ether phospholipid accumulation.

The widespread environmental presence of nanoplastics (NPs) raises significant concerns about their health impacts, particularly on the gastrointestinal system, as NPs are primarily ingested. While previous studies have linked NP-induced intestinal toxicity to oxidative stress and reactive oxygen species (ROS) accumulation, the specific mechanisms of cell death remain unclear. Here, we showed that environmentally relevant concentrations of polystyrene nanoplastics (PS-NPs) induced ferroptosis, a form of lipid peroxidation-driven cell death, in intestinal epithelial cells.

The effectiveness of individualized blood flow restriction training following patellar fracture surgery: a case series.

Background: Patellar fracture surgeries are associated with subsequent atrophy and weakness in the muscles of the lower limb. Individualized blood flow restriction training is progressively being recognized as a potential technique for improving muscular hypertrophy and accompanying strength in participants recovering from surgery. This study aimed to investigate the overall feasibility and observational outcomes of individualized blood flow restriction training for participants recovering from patellar fracture surgery.