Publications by authors named "B H Harmon"

Background: Children and youth with special health care needs (CYSHCN) may be at greater risk for accidental physical trauma. Interventions should be informed by the literature indicating incident characteristics and at-risk subpopulations.

Objective: To conduct a scoping review of accidental physical trauma in CYSHCN to characterize published literature and identify gaps.

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Background: Ductal carcinoma in situ (DCIS) is a non-obligate precursor to invasive breast cancer (IBC). Studies have indicated differences in DCIS outcome based on race or ethnicity, but molecular differences have not been investigated.

Methods: We examined the molecular profile of DCIS by self-reported race (SRR) and outcome groups in Black (n = 99) and White (n = 191) women in a large DCIS case-control cohort study with longitudinal follow up.

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Article Synopsis
  • RSV bronchiolitis is a serious condition affecting infants worldwide, and the study investigates the role of microRNA (miRNA) in determining disease severity.
  • Researchers analyzed the upper airway miRNA and mRNA of 493 hospitalized infants to find specific miRNAs and mRNAs linked to more severe cases that required advanced respiratory support.
  • The findings identified 19 key miRNAs and numerous biological pathways associated with bronchiolitis severity, revealing a complex network of gene interactions that could inform future treatments.
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HPV infections are associated with a fraction of vulvar cancers. Through hybridization capture and DNA sequencing, HPV DNA was detected in five of thirteen vulvar cancers. HPV16 DNA was integrated into human DNA in three of the five.

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This paper describes the development of a first- and second-year inquiry-based laboratory course focused on the development of a meaningful application of intermolecular forces (IMFs). Instead of broad expository coverage of topics, we used backward design: the techniques and concepts for the course were structured around what students are expected to be able to do at the end-individually isolate caffeine from a consumer product as a culminating lab practical, using IMFs to justify solvent choices and determining procedural details. We have found that instructors can select a challenging multilevel experiment that incorporates the application of IMFs in multiple ways and backward design the course so that students are able to complete this experiment individually and autonomously at the end of the semester.

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