Evaluating the tolerance of harmful algal bloom communities to copper.

Harmful algal blooms (HABs) cause severe economic and environmental impacts, including hypoxic events and the production of toxins and off-flavor compounds. Chemical treatments, such as copper sulfate pentahydrate (CuSO·5HO), are often used to mitigate the damaging effects of algal blooms. However, treatment effects are usually short-lived leading to waterbodies requiring repeated CuSO·5HO applications to control persistent algal blooms, particularly in highly eutrophic systems, such as aquaculture ponds or small agricultural impoundments.

Triply Ordered 6H Halide Perovskites: A Family of Triangular Lattice Antiferromagnets.

Three new hexagonal perovskites with CsMMRhCl (M = Na, Ag; M = Mn, Fe) stoichiometry have been synthesized from solution precipitation reactions. These air-stable compounds crystallize as triply cation-ordered variants of the 6H perovskite structure. This structure contains octahedra that share a common face to form MRhCl dimers that are arranged on a two-dimensional triangular network.

Trends in alcohol, MDMA, methylamphetamine and THC in injured and deceased motor vehicle drivers and motorcyclists over a decade (2010-2019) in Victoria, Australia.

Background: Driving under the influence of alcohol and other drugs contributes significantly to road traffic crashes worldwide. This study explored trends of alcohol, methylamphetamine (MA), 3,4-methylenedioxy-N-methylamphetamine (MDMA) and Δ9-tetrahydrocannabinol (THC), in road crashes from 2010 to 2019 in Victoria, Australia.

Methods: We conducted a cross-sectional analysis using data from the Victorian Institute of Forensic Medicine and Victoria Police, examining proscribed drug detections in road crashes.

Effective Newborn Screening for Type 1 and 3 Primary Hyperoxaluria.

Introduction: Newborn screening (NBS) programs for a defined set of eligible diseases have been enormously successful, but genomic NBS allowing for detection of additional treatable disorders has not been broadly implemented. All 3 types of primary hyperoxaluria (PH1-3) are rare autosomal recessive diseases caused by distinct defects of glyoxylate metabolism that are diagnosed genetically with certainty. Early diagnosis and treatment are mandatory to avoid renal failure or sequalae associated with persistent hyperoxaluria.

A cell-based Papain-like Protease (PLpro) activity assay for rapid detection of active SARS-CoV-2 infections and antivirals.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants are a continuous threat to human life. An urgent need remains for simple and fast tests that reliably detect active infections with SARS-CoV-2 and its variants in the early stage of infection. Here we introduce a simple and rapid activity-based diagnostic (ABDx) test that identifies SARS-CoV-2 infections by measuring the activity of a viral enzyme, Papain-Like protease (PLpro).